conditional gene knockout

conditional gene knockout
обусловленный (условиями) нокаут гена

English-Russian Biotechnology Glossary. . 2007.

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  • Conditional gene knockout — is a relatively new technique, an offshoot of gene knockout technology with the exception that a specific target gene is eliminated from a single organ in the body rather than the whole body as gene knockout technology would entail. Thus this… …   Wikipedia

  • Gene knockout — A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism s genes is made inoperative ( knocked out of the organism). Also known as knockout organisms or simply knockouts, they are used in learning about a gene that… …   Wikipedia

  • Knockout rats — Knockout rats=A knockout rat is a rat with a single gene disruption used for academic and pharmaceutical research. Knockout rats can mimic human diseases and are important tools for studying gene function (functional genomics) and for drug… …   Wikipedia

  • Knockout mouse — A knockout mouse is a genetically engineered mouse in which one or more genes have been turned off through a gene knockout. Knockout mice are important animal models for studying the role of genes which have been sequenced, but have unknown… …   Wikipedia

  • Gene targeting — NOTOC Gene targeting (also, replacement strategy based on homologous recombination) is a genetic technique that uses homologous recombination to change an endogenous gene. The method can be used to delete a gene, remove exons, and introduce point …   Wikipedia

  • International Knockout Mouse Consortium — IKMC: International Knockout Mouse Consortium Content Description International Knockout Mouse Consortium Organism(s) Mice …   Wikipedia

  • Glossary of gene expression terms — See also: gene expression, List of Glossaries, List of Natural Sciences Glossaries A*Activator protein that binds to an enhancer (or activator binding region) and activates transcription from nearby promoter.*A DNA a form of DNA found at low… …   Wikipedia

  • Reverse genetics — is an approach to discovering the function of a gene that proceeds in the opposite direction of so called forward genetic screens of classical genetics. Simply put, while forward genetics seeks to find the genetic basis of a phenotype or trait,… …   Wikipedia

  • Сусуму Тонэгава — (Susumu Tonegawa, 利根川 進) (6.09.1939 …) нобелевский лауреат родом из Японии Направление Медицина и физиология (1987 год) За что? «За открытие генетического принципа для генерации разновидности антител» Страна, которую представляет США Институт,… …   Википедия

  • Mothers against decapentaplegic homolog 4 — SMAD family member 4 PDB rendering based on 1dd1 …   Wikipedia

  • Tetracycline controlled transcriptional activation — is a method of inducible expression where transcription is reversibly turned on or off in the presence of the antibiotic tetracycline or one of its derivatives (etc. doxycycline). In nature, pTet promotes TetR, the repressor, and TetA, the… …   Wikipedia


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